In Unit 2, students explore the day-to-day operations of a primary care office. Students will take on the role of primary care physicians and visit with a series of patients. Along the way, they will compile resources to create a formal report containing patient files from each individual lesson. Throughout the unit, they will explore case studies of Type 1 Diabetes, basal cell carcinoma, neurofibromatosis, chromosomal abnormalities, and familial hypercholesterolemia. In Lesson 1 (9-10 blocks), students will learn how to conduct a doctor’s visit and fill out a patient chart. They will start by conducting interviews to learn a patient’s medical history and then take vital signs, and simulate routine testing done both in the office and in the lab. They will then consider aspects of primary healthcare including telehealth and patient privacy. In Lesson 2 (11-12 blocks), students will build on their learning in Lesson 1 by using their simulated patient information and test results to determine a diagnosis and provide recommendations for next steps. Students explore the processes of mitosis, meiosis, and protein synthesis as they visit with patients with cancer and chromosomal abnormalities. They learn how genetic disorders are inherited and construct pedigrees representing their patients’ families. In Lesson 3 (2-3 blocks), students put together everything they have learned in the unit to meet and diagnose a new patient from start to finish. At the end of the unit, students will submit their final culmination of patient files as a formal report.